This systematic review and meta-analysis included 22 randomized controlled trials comprising 2,354 patients. The combination of acoustics and cognitive behavioral therapy may be an effective way to treat patients with chronic tinnitus.

References: Lu T, Wang Q, Gu Z, Li Z, Yan Z. Non-invasive treatments improve patient outcomes in chronic tinnitus: a systematic review and network meta-analysis. Braz J Otorhinolaryngol. 2024 Jul-Aug;90(4):101438. doi: 10.1016/j.bjorl.2024.101438. Epub 2024 May 2. PMID: 38788246; PMCID: PMC11143903.

13 eligible RTs with a total of 1345 patients were included in this meta-analysis. The meta-analysis results showed that the 1-month response rate, 3-month response rate, 6-month response rate, and overall response rate of TRT with drugs for tinnitus were higher than that of drugs only (P < 0.05). The results demonstrated that the THI (Tinnitus Handicap Inventory) scale after the treatment period of TRT with medications for tinnitus was lower than that of drugs only (P < 0.05).

References: Han M, Yang X, Lv J. Efficacy of tinnitus retraining therapy in the treatment of tinnitus: A meta-analysis and systematic review. Am J Otolaryngol. 2021 Nov-Dec;42(6):103151. doi: 10.1016/j.amjoto.2021.103151. Epub 2021 Jun 27. PMID: 34303210.

Studies have provided evidence that Hearing Aid fitting is a valuable treatment strategy for chronic tinnitus relief with associated hearing loss.

References: 1) Simonetti P, Vasconcelos LG, Gândara MR, Lezirovitz K, Medeiros ÍRT, Oiticica J. Hearing aid effectiveness on patients with chronic tinnitus and associated hearing loss. Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 3(Suppl 3):S164-S170. doi: 10.1016/j.bjorl.2022.03.002. Epub 2022 May 20. PMID: 35729042; PMCID: PMC9761006. 2) Lee HJ, Kang DW, Yeo SG, Kim SH. Hearing Aid Effects and Satisfaction in Patients with Tinnitus. J Clin Med. 2022 Feb 18;11(4):1096. doi: 10.3390/jcm11041096. PMID: 35207368; PMCID: PMC8875221.